Cryptic crossword clue
One with domestic charge could be former PM’s successful aide? 9

The most common and most likely answer to this crossword clue is the 9 letter word HOMEMAKER

H
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Buddy explains!

The straight part
We know that "One with domestic charge" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one with domestic charge = homemaker.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HOMEMAKER mean?

HOMEMAKER noun
  1. A person who maintains the administration and upkeep of his or her residence, especially one who is not employed outside the home; one who runs the household.

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