Cryptic crossword clue
One’s cross, drawn into horseplay with practical jokers 7

The most common and most likely answer to this crossword clue is the 7 letter word HOAXERS

I've seen this crossword clue in Financial Times
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Buddy explains!

The straight part
We know that "practical jokers" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case practical jokers = hoaxers.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HOAXERS mean?

HOAXERS noun
  1. Someone who perpetrates hoaxes.

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