Cryptic crossword clue
Open-air sex at assembly causes annoyance

The most common and most likely answer to this crossword clue is the 12 letter word EXASPERATION

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "annoyance" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case annoyance = exasperation.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EXASPERATION mean?

EXASPERATION noun
  1. The act of exasperating or the state of being exasperated; irritation; keen or bitter anger.
  2. Increase of violence or malignity; aggravation; exacerbation.

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