Cryptic crossword clue
Open with a sign that something’s wrong — stress too much 7

The most common and most likely answer to this crossword clue is the 7 letter word OVERTAX

I've seen this crossword clue in The Daily Telegraph
O
V
E
R
T
A
X


Buddy explains!

The straight part
We know that "stress too much" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case stress too much = overtax.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does OVERTAX mean?

OVERTAX verb
  1. To tax to an excessive degree
  2. To overburden

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