The most common and most likely answer to this crossword clue is the 6 letter word BEGINS
I've seen this crossword clue in The Times
B
E
G
I
N
S
More clues leading to the result BEGINS
Buddy explains!
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does BEGINS mean?
BEGINS verb- To start, to initiate or take the first step into something.
- To be in the first stage of some situation
- To come into existence.