Cryptic crossword clue
Opera for example, without work returned to assimilate again 6

The most common and most likely answer to this crossword clue is the 6 letter word RESORB

R
E
S
O
R
B

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The straight part
We know that "assimilate again" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case assimilate again = resorb.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RESORB mean?

RESORB verb
  1. To absorb (something) again.
  2. To undergo resorption.
  3. To dissolve (bone, sinew, suture, etc.) and assimilate it.

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