The most common and most likely answer to this crossword clue is the 8 letter word SURGEONS
I've seen this crossword clue in The Daily Telegraph
S
U
R
G
E
O
N
S
More clues leading to the result SURGEONS
Buddy explains!

The straight part
We know that "Operators" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case operators = surgeons.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SURGEONS mean?
SURGEONS noun- One who performs surgery; a doctor who performs operations on people or animals.
- A surgeonfish.