Cryptic crossword clue
Organ of father sick in the middle 7

The most common and most likely answer to this crossword clue is the 7 letter word PAPILLA

P
A
P
I
L
L
A

Buddy explains!

The straight part
We know that "Organ" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case organ = papilla.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PAPILLA mean?

PAPILLA noun
  1. A nipple-like anatomical structure.

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