Cryptic crossword clue
Organelle initially released in intimate ecstasy 8

The most common and most likely answer to this crossword clue is the 8 letter word RIBOSOME

R
I
B
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O
M
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Buddy explains!

The straight part
We know that "Organelle" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case organelle = ribosome.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RIBOSOME mean?

RIBOSOME noun
  1. A small organelle found in all cells; involved in the production of proteins by translating messenger RNA.

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