Cryptic crossword clue
Original shots, say, drunk by locals 9

The most common and most likely answer to this crossword clue is the 9 letter word NEGATIVES

I've seen this crossword clue in The Times
N
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Buddy explains!

The straight part
We know that "Original shots" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case original shots = negatives.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does NEGATIVES mean?

NEGATIVES noun
  1. Refusal or withholding of assents; prohibition, veto
  2. A right of veto.
  3. An image in which dark areas represent light ones, and the converse.
  4. (grammar) A word that indicates negation.
  5. A negative quantity.
  6. : A rep performed with weight in which the muscle begins at maximum contraction and is slowly extended; a movement performed using only the eccentric phase of muscle movement.
  7. The negative plate of a voltaic or electrolytic cell.
NEGATIVES verb
  1. To refuse; to veto.
  2. To contradict.
  3. To disprove.
  4. To make ineffective; to neutralize.

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