The most common and most likely answer to this crossword clue is the 2 plus 6 letter word ON STRIKE
I've seen this crossword clue in Financial Times
O
N
S
T
R
I
K
E
Buddy explains!

The straight part
We know that "Out" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case out = on strike.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.