Cryptic crossword clue
Out getting bread mix, deaf to all advice 8

The most common and most likely answer to this crossword clue is the 8 letter word OBDURATE

I've seen this crossword clue in The Guardian
O
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Buddy explains!

The straight part
We know that "deaf to all advice" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case deaf to all advice = obdurate.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does OBDURATE mean?

OBDURATE verb
  1. To harden; to obdure.
OBDURATE adjective
  1. Stubbornly persistent, generally in wrongdoing; refusing to reform or repent.
  2. Physically hardened, toughened.
  3. Hardened against feeling; hard-hearted.

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