Cryptic crossword clue
Out of her mind, poor Maxine, with love 2,5

The most common and most likely answer to this crossword clue is the 2 plus 5 letter word EX ANIMO

I've seen this crossword clue in Independent
E
X
A
N
I
M
O

Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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