Cryptic crossword clue
Over there temperature painfully affected the lady 7

The most common and most likely answer to this crossword clue is the 7 letter word THITHER

T
H
I
T
H
E
R

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The straight part
We know that "Over there" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case over there = thither.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does THITHER mean?

THITHER adjective
  1. The farther, the other and more distant.
THITHER adverb
  1. To that place.
  2. To that point, end, or result.

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