Cryptic crossword clue
Overthrow annulment

The most common and most likely answer to this crossword clue is the 6 letter word DEFEAT

I've seen this crossword clue in Independent
D
E
F
E
A
T


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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DEFEAT mean?

DEFEAT verb
  1. To overcome in battle or contest.
  2. To reduce, to nothing, the strength of.
  3. To nullify
DEFEAT noun
  1. The act or instance of being defeated, of being overcome or vanquished; a loss.
  2. The act or instance of defeating, of overcoming, vanquishing.
  3. Frustration (by prevention of success), stymieing; nullification.
  4. Destruction, ruin.

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