Cryptic crossword clue
Overturns positive results 6

The most common and most likely answer to this crossword clue is the 6 letter word UPENDS

U
P
E
N
D
S

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does UPENDS mean?

UPENDS verb
  1. To end up; to set on end.
  2. To tip or turn over.
  3. To destroy, invalidate, overthrow, or defeat.

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