Cryptic crossword clue
Oxygenated 3 in de-oxygenated channels? 6

The most common and most likely answer to this crossword clue is the 6 letter word VENOUS

I've seen this crossword clue in The Guardian
V
E
N
O
U
S


Buddy explains!

The straight part
We know that "in de-oxygenated channels" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case in de-oxygenated channels = venous.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does VENOUS mean?

VENOUS adjective
  1. Of or pertaining to veins.
  2. Possessing veins.
  3. Having numerous veins.

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