The most common and most likely answer to this crossword clue is the 7 letter word EARACHE
I've seen this crossword clue in The Daily Telegraph
E
A
R
A
C
H
E
More clues leading to the result EARACHE
- It hurts, being long subordinate to judge in Bow
- Complaint demanding attention by a guerrilla leader
- English with a passé dog could be a pain
- Drops the answer to this listener's complaint?
- Teacher avoiding extremes, describing artist’s pain
- Middle and inner organ pain are each different
- Pain given by gunman in every way
- A race he organised would keep you awake
- Bill after attention? The man’s a pain
- Clear a cheque, admitting a minor complaint
Buddy explains!

The straight part
We know that "Pain" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case pain = earache.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does EARACHE mean?
EARACHE noun- A pain in the middle or inner ear.