Cryptic crossword clue
Pain from running, perhaps — affected after covering run 5

The most common and most likely answer to this crossword clue is the 5 letter word CRAMP

I've seen this crossword clue in The Times
C
R
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Buddy explains!

The straight part
We know that "Pain from running, perhaps" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case pain from running, perhaps = cramp.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CRAMP mean?

CRAMP noun
  1. A painful contraction of a muscle which cannot be controlled.
  2. That which confines or contracts; a restraint; a shackle; a hindrance.
  3. A clamp for carpentry or masonry.
  4. A piece of wood having a curve corresponding to that of the upper part of the instep, on which the upper leather of a boot is stretched to give it the requisite shape.
CRAMP verb
  1. (of a muscle) To contract painfully and uncontrollably.
  2. To affect with cramps or spasms.
  3. To prohibit movement or expression of.
  4. To restrain to a specific physical position, as if with a cramp.
  5. To fasten or hold with, or as if with, a cramp iron.
  6. (by extension) To bind together; to unite.
  7. To form on a cramp.
CRAMP adjective
  1. Cramped; narrow

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