Cryptic crossword clue
Pain killers striving after final change 8

The most common and most likely answer to this crossword clue is the 8 letter word ASPIRINS

A
S
P
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ASPIRINS mean?

ASPIRINS noun
  1. An analgesic drug, acetylsalicylic acid
  2. A tablet containing this substance

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