Cryptic crossword clue
Panacea reps flogged? Many try to keep them up 11

The most common and most likely answer to this crossword clue is the 11 letter word APPEARANCES

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Buddy explains!

The straight part
We know that "Many try to keep them up" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case many try to keep them up = appearances.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does APPEARANCES mean?

APPEARANCES noun
  1. The act of appearing or coming into sight; the act of becoming visible to the eye.
  2. A thing seen; a phenomenon; an apparition.
  3. The way something looks; personal presence
  4. Apparent likeness; the way which something or someone appears to others.
  5. That which is not substance, essence, hypostasis; the outward reality as opposed to the underlying reality
  6. The act of appearing in a particular place, or in society, a company, or any proceedings; a coming before the public in a particular character.
  7. An instance of someone coming into a court of law to be part of a trial, either in person or represented by an attorney or such like; a court appearance
  8. Chiefly used by nurses: the act of defecation by a patient.

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