The most common and most likely answer to this crossword clue is the 6 letter word HIATUS
I've seen this crossword clue in The Daily Telegraph
H
I
A
T
U
S
More clues leading to the result HIATUS
- In break, shout greeting in our direction
- Greeting coming in our direction in break
- Success by American boxing amateur offers a break
- Break America after success touring Austria
- Strike American defending a gap
- Break hearts in this way, splitting trousers
- America after success to bridge a gap
- Welcome to America for break
- Break South American state holding one back
- Sample sushi at usual interval
Buddy explains!

The straight part
We know that "interruption" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case interruption = hiatus.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does HIATUS mean?
HIATUS noun- A gap in a series, making it incomplete.
- An interruption, break or pause.
- An unexpected break from work.
- A gap in geological strata.
- An opening in an organ.
- A syllable break between two vowels, without an intervening consonant. (Compare diphthong.)