The most common and most likely answer to this crossword clue is the 5 letter word SHANK
I've seen this crossword clue in The Times
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Buddy explains!

The straight part
We know that "Part of leg/mishit ball" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case part of leg/mishit ball = shank.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SHANK mean?
SHANK noun- The part of the leg between the knee and the ankle.
- Meat from that part of an animal.
- A redshank or greenshank, various species of Old World wading birds in the genus Tringa having distinctly colored legs.
- A straight, narrow part of an object, such as a key or an anchor; shaft; stem.
- The handle of a pair of shears, connecting the ride to the neck.
- The center part of a fishhook between the eye and the hook, the 'hook' being the curved part that bends toward the point.
- A protruding part of an object, by which it is or can be attached.
- The metal part on a curb bit that falls below the mouthpiece, which length controls the severity of the leverage action of the bit, and to which the reins of the bridle are attached.
- A poorly played golf shot in which the ball is struck by the part of the club head that connects to the shaft.
- An improvised stabbing weapon; a shiv.
- A loop forming an eye to a button.
- The space between two channels of the Doric triglyph.
- A large ladle for molten metal, fitted with long bars for handling it.
- The body of a type; between the shoulder and the foot.
- (shoemaking) The part of the sole beneath the instep connecting the broader front part with the heel.
- Flat-nosed pliers, used by opticians for nipping off the edges of pieces of glass to make them round.
- The end or remainder, particularly of a period of time.
- The main part or beginning of a period of time.
- To travel on foot.
- To stab, especially with an improvised blade.
- To remove another's trousers, especially in jest; to depants.
- To misstrike the ball with the part of the club head that connects to the shaft.
- To hit or kick the ball in an unintended direction.
- To fall off, as a leaf, flower, or capsule, on account of disease affecting the supporting footstalk; usually followed by off.
- To provide (a button) with a shank (loop forming an eye).
- (shoemaking) To apply the shank to a shoe, during the process of manufacturing it.
- Bad.