The most common and most likely answer to this crossword clue is the 4 letter word ISIS
I've seen this crossword clue in Independent
I
S
I
S
More clues leading to the result ISIS
- Two islands in river
- Goddess: I’m Swiss, oddly
- Isaiah represents divinity
- India with little girl seen as a goddess
- Time of difficulty, not leading pair to find goddess
- Goddess losing credit in moment of truth
- River one’s come across twice
- Punters here in big trouble after credit's withdrawn
- Revered figure with multiple lives
- Goddess lives on island
Buddy explains!
The straight part
We know that "Part of River" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case part of river = isis.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.