Cryptic crossword clue
Part of the skeleton absent or damaged — live without it 10

The most common and most likely answer to this crossword clue is the 10 letter word BREASTBONE

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Buddy explains!

The straight part
We know that "Part of the skeleton" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case part of the skeleton = breastbone.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BREASTBONE mean?

BREASTBONE noun
  1. The central narrow bone in the front of the chest, connecting the collarbone and the top ribs.

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