The most common and most likely answer to this crossword clue is the 5 letter word UNARM
U
N
A
R
M
More clues leading to the result UNARM
- Strip protection from team without right back
- Make harmless run through football team making comeback
- Make harmless, primarily racy cracks revolting football team
- Remove weapons from section of lunar module
- Partially stun armadillo to render harmless
- Remove weapons from one French Arab male
- Disable one Italian female, room vacated
- Remove something potentially harmful from part of lunar module
- Withdraw protection from force trailing an Italian
- One in Paris has weapon to take away
Buddy explains!

The straight part
We know that "render harmless" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case render harmless = unarm.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does UNARM mean?
UNARM verb- To disarm, to remove the armour and weapons from.
- To remove one's armour.