Cryptic crossword clue
Particles found in 40% of surgical procedures 4

The most common and most likely answer to this crossword clue is the 4 letter word IONS

I
O
N
S


Buddy explains!

The straight part
We know that "Particles" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case particles = ions.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does IONS mean?

IONS noun
  1. An atom or group of atoms bearing an electrical charge, such as the sodium and chlorine atoms in a salt solution.

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