The most common and most likely answer to this crossword clue is the 6 letter word DOPING
I've seen this crossword clue in Independent
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More clues leading to the result DOPING
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The straight part
We know that "taking drugs" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case taking drugs = doping.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DOPING mean?
DOPING verb- To affect with drugs.
- To treat with dope (lubricant, etc.).
- To add a dopant such as arsenic to (a pure semiconductor such as silicon).
- To use drugs; especially, to use prohibited performance-enhancing drugs in sporting competitions.
- To judge or guess; to predict the result of.
- The use of drugs to improve athletic performance.
- The addition of small quantities of an element (a dopant) to a semiconductor to change its characteristics.