Cryptic crossword clue
Party inflicting damage around River Wye, initially

The most common and most likely answer to this crossword clue is the 13 letter word HOUSE-WARMING

I've seen this crossword clue in The Guardian
H
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Buddy explains!

The straight part
We know that "Party" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case party = house-warming.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HOUSE-WARMING mean?

HOUSE-WARMING noun
  1. A party to celebrate moving into a new home.
  2. The act of welcoming a person/family to their newly purchased or newly rented home.

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