Cryptic crossword clue
Party member that infuriated the Queen 6

The most common and most likely answer to this crossword clue is the 6 letter word HATTER

I've seen this crossword clue in The Guardian
H
A
T
T
E
R

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The straight part
We know that "Party member" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case party member = hatter.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HATTER mean?

HATTER noun
  1. A person who makes, sells, or repairs hats.
  2. A person who lives alone in the bush.
  3. A miner who works by himself.
HATTER verb
  1. To tire or worry.

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