Cryptic crossword clue
Patch on last sore to be treated, limb not good 6

The most common and most likely answer to this crossword clue is the 6 letter word RESOLE

R
E
S
O
L
E

Buddy explains!

The straight part
We know that "Patch on last" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case patch on last = resole.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RESOLE mean?

RESOLE verb
  1. To replace or reattach the sole of an article of footwear.

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