The most common and most likely answer to this crossword clue is the 10 letter word TOLERATION
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The straight part
We know that "Patience" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case patience = toleration.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does TOLERATION mean?
TOLERATION noun- Endurance of evil, suffering etc.
- The allowance of something not explicitly approved; tolerance, forbearance.
- Specifically, the allowance by a government (or other ruling power) of the exercise of religion beyond the state established faith.