Cryptic crossword clue
Patient held very tight breathed very heavily 15

The most common and most likely answer to this crossword clue is the 15 letter word HYPERVENTILATED

I've seen this crossword clue in The Daily Telegraph
H
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Buddy explains!

The straight part
We know that "breathed very heavily" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case breathed very heavily = hyperventilated.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HYPERVENTILATED mean?

HYPERVENTILATED verb
  1. To breathe quickly and deeply, especially at an abnormally rapid rate.

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