The most common and most likely answer to this crossword clue is the 2 letter word PC
I've seen this crossword clue in The Guardian
P
C
More clues leading to the result PC
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does PC mean?
PC noun- A percentage, a proportion (especially per hundred).
- One part per hundred; one percent.
- A part of a larger whole, usually in such a form that it is able to be separated from other parts.
- A single item belonging to a class of similar items
- One of the figures used in playing chess, specifically a higher-value figure as distinguished from a pawn; by extension, a similar counter etc. in other games.
- A coin, especially one valued at less than the principal unit of currency.
- An artistic creation, such as a painting, sculpture, musical composition, literary work, etc.
- An article published in the press.
- An artillery gun.
- A gun.
- (short for hairpiece) A toupee or wig, especially when worn by a man.
- A slice or other quantity of bread, eaten on its own; a sandwich or light snack.
- A sexual encounter; from piece of ass or piece of tail
- (mildly, short for piece of crap/piece of shit) A shoddy or worthless object (usually applied to consumer products like vehicles or appliances).
- A cannabis pipe.
- Used to describe a pitch that has been hit but not well, usually either being caught by the opposing team or going foul. Usually used in the past tense with got.
- (sometimes derogatory) An individual; a person.
- A castle; a fortified building.
- A pacifier; a dummy.
- A distance.
- A structured practice row, often used for performance evaluation.
- An amount of work to be done at one time; a unit of piece work.
- A rectangular piece of thick paper or thin cardboard intended to be written on and mailed without an envelope. In the case of a picture postcard one side carries a picture or photograph.