The most common and most likely answer to this crossword clue is the 3 plus 7 letter word SEE THROUGH
I've seen this crossword clue in The Times
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More clues leading to the result SEE THROUGH
Buddy explains!

The straight part
We know that "Perceive the true nature of/transparent" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case perceive the true nature of/transparent = see through.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SEE THROUGH mean?
SEE THROUGH adjective- Transparent or translucent; that can be seen through