The most common and most likely answer to this crossword clue is the 5 letter word QUICK
I've seen this crossword clue in The Guardian
Q
U
I
C
K
More clues leading to the result QUICK
- Perfunctory “medic” with heart replacement
- Painfully sensitive flesh lasting a short time
- Nimble comedian Edward having an alert mind
- Hasty Queen beheaded devil
- Ready source of evidence about Edward showing mental agility
- Command — fast over 31 days
- Fast living
- An impermanent fix?
- Rapid repair is only temporary
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does QUICK mean?
QUICK noun- Raw or sensitive flesh, especially that underneath finger and toe nails.
- Plants used in making a quickset hedge
- The life; the mortal point; a vital part; a part susceptible to serious injury or keen feeling.
- Quitchgrass.
- A fast bowler.
- To amalgamate surfaces prior to gilding or silvering by dipping them into a solution of mercury in nitric acid.
- To quicken.
- Moving with speed, rapidity or swiftness, or capable of doing so; rapid; fast.
- Occurring in a short time; happening or done rapidly.
- Lively, fast-thinking, witty, intelligent.
- Mentally agile, alert, perceptive.
- Of temper: easily aroused to anger; quick-tempered.
- Alive, living.
- Pregnant, especially at the stage where the foetus's movements can be felt; figuratively, alive with some emotion or feeling.
- Of water: flowing.
- Burning, flammable, fiery.
- Fresh; bracing; sharp; keen.
- (of a vein of ore) productive; not "dead" or barren
- Quickly, in a quick manner.