Cryptic crossword clue
Periods of European disease causing skin rash, reportedly 6

The most common and most likely answer to this crossword clue is the 6 letter word EPOCHS

I've seen this crossword clue in The Daily Telegraph
E
P
O
C
H
S


Buddy explains!

The straight part
We know that "Periods" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case periods = epochs.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EPOCHS mean?

EPOCHS noun
  1. A particular period of history, especially one considered noteworthy or remarkable.
  2. A notable event which marks the beginning of such a period.
  3. A precise instant of time that is used as a point of reference.
  4. Uses in computing.
  5. A unit of geologic time subdividing a period into smaller parts.

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