Cryptic crossword clue
Permanence of ill repute — shame about that 10

The most common and most likely answer to this crossword clue is the 10 letter word PERPETUITY

I've seen this crossword clue in The Times
P
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Buddy explains!

The straight part
We know that "Permanence" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case permanence = perpetuity.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PERPETUITY mean?

PERPETUITY noun
  1. The quality or state of being perpetual; endless duration; uninterrupted existence.
  2. Something that is perpetual.
  3. A limitation intended to be unalterable and of indefinite duration; a disposition of property which attempts to make it inalienable beyond certain limits fixed or conceived as being fixed by the general law.
  4. An annuity in which the periodic payments begin on a fixed date and continue indefinitely.

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