Cryptic crossword clue
Permit Oslo or Rome to slip badly as big city 10

The most common and most likely answer to this crossword clue is the 10 letter word METROPOLIS

M
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Buddy explains!

The straight part
We know that "big city" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case big city = metropolis.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does METROPOLIS mean?

METROPOLIS noun
  1. (history) The mother (founding) polis (city state) of a colony.
  2. A large, busy city, especially as the main city in an area or country or as distinguished from surrounding rural areas.
  3. (canon law) The see of a metropolitan archbishop, ranking above its suffragan diocesan bishops.
  4. A generic focus in the distribution of plants or animals.

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