The most common and most likely answer to this crossword clue is the 4 plus 3 letter word UNCE SAM
I've seen this crossword clue in The Sunday Telegraph
U
N
C
E
S
A
M
Buddy explains!
The straight part
We know that "Personification of great power" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case personification of great power = unce sam.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.