Cryptic crossword clue
Picture of brain spread around, coating new mushroom ring 13

The most common and most likely answer to this crossword clue is the 13 letter word ENCEPHALOGRAM

I've seen this crossword clue in The Guardian
E
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Buddy explains!

The straight part
We know that "Picture of brain" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case picture of brain = encephalogram.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ENCEPHALOGRAM mean?

ENCEPHALOGRAM noun
  1. An image of the brain obtained by encephalography.

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