The most common and most likely answer to this crossword clue is the 5 letter word JIHAD
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More clues leading to the result JIHAD
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The cryptic/wordplay part
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What does JIHAD mean?
JIHAD noun- A holy war undertaken by Muslims.
- An aggressive campaign for an idea.
- A personal spiritual struggle for self-improvement and/or against evil.
- To participate in a jihad.