Cryptic crossword clue
Plant disease checked by English fellow’s universal remedy 4-3

The most common and most likely answer to this crossword clue is the 8 letter word CURE-ALL

I've seen this crossword clue in Independent
C
U
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A
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Buddy explains!

The straight part
We know that "universal remedy" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case universal remedy = cure-all.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CURE-ALL mean?

CURE-ALL noun
  1. A panacea.

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