The most common and most likely answer to this crossword clue is the 10 letter word HYPERMEDIA
I've seen this crossword clue in The Guardian
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Buddy explains!
The straight part
We know that "interactive information system" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case interactive information system = hypermedia.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does HYPERMEDIA mean?
HYPERMEDIA noun- The use of text, data, graphics, audio and video as elements of an extended hypertext system in which all elements are linked so that the user can move among them at will