Cryptic crossword clue
Poisonous, half a dozen law books 8

The most common and most likely answer to this crossword clue is the 8 letter word VIRULENT

I've seen this crossword clue in The Sunday Telegraph
V
I
R
U
L
E
N
T

Buddy explains!

The straight part
We know that "Poisonous," is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case poisonous, = virulent.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does VIRULENT mean?

VIRULENT adjective
  1. (of a disease or disease-causing agent) Highly infectious, malignant or deadly.
  2. Hostile to the point of being venomous; intensely acrimonious.

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