Cryptic crossword clue
Polite matron, refined, characteristic of London perhaps? 12

The most common and most likely answer to this crossword clue is the 12 letter word METROPOLITAN

I've seen this crossword clue in Financial Times
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Buddy explains!

The straight part
We know that "characteristic of London perhaps" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case characteristic of london perhaps = metropolitan.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does METROPOLITAN mean?

METROPOLITAN noun
  1. A bishop empowered to oversee other bishops; an archbishop.
  2. The inhabitant of a metropolis.
METROPOLITAN adjective
  1. Pertaining to the see or province of a metropolitan.
  2. Of, or pertaining to, a metropolis or other large urban settlement.

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