The most common and most likely answer to this crossword clue is the 8 letter word IMPETIGO
I've seen this crossword clue in The Daily Telegraph
I
M
P
E
T
I
G
O
More clues leading to the result IMPETIGO
- Infection of one’s darling — getting one shot
- Time pig suffered with old disease
- I met GP for treatment involving one old skin complaint
- 4 across’s 4 across, perhaps, 4 across to leave skin infection
- Current GP with time to treat ordinary skin problem
- Not a fatal disease but one I’m to peg out from
- This compiler’s tame current work generates complaint
- Poorly MEP taken in by Italian needing single shot for infection
- Condition of motorway on the way up, dear? I leave
- The compiler’s favourite function, accepting current complaint
Buddy explains!

The straight part
We know that "infection" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case infection = impetigo.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does IMPETIGO mean?
IMPETIGO noun- A contagious bacterial skin disease forming pustules and yellow crusty sores, chiefly on the face and hands. It is common in children and infection is often through cuts or insect bites.