Cryptic crossword clue
Port drunk with chasers -— it gets you very high 13

The most common and most likely answer to this crossword clue is the 13 letter word STRATOSPHERIC

I've seen this crossword clue in The Guardian
S
T
R
A
T
O
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P
H
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C

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does STRATOSPHERIC mean?

STRATOSPHERIC adjective
  1. Of, relating to, or occurring in the stratosphere.
  2. Unusually or unreasonably high; astronomical.

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