The most common and most likely answer to this crossword clue is the 9 letter word CURIOSITY
I've seen this crossword clue in The Guardian
C
U
R
I
O
S
I
T
Y
Buddy explains!

The straight part
We know that "interest" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case interest = curiosity.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does CURIOSITY mean?
CURIOSITY noun- (uncountable) Inquisitiveness; the tendency to ask and learn about things by asking questions, investigating, or exploring.
- A unique or extraordinary object which arouses interest.
- Careful, delicate construction; fine workmanship, delicacy of building.