The most common and most likely answer to this crossword clue is the 4 letter word DYKE
D
Y
K
E
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DYKE mean?
DYKE noun- (usually derogatory) A lesbian, particularly one with masculine or butch traits or behavior.